November 2020

What are the effects of having long term uveitis? Are flares the only time to worry about? Do eyes degrade similar to joints?

By |November 9th, 2020|, |

Long term effects of uveitis can be minimized by prompt diagnosis, consistent monitoring, and appropriate use of medications.  Some of the main effects that can occur and which we try to avoid with therapy include the following: Decrease in vision:  When there is inflammation in the eye, such as occurs with uveitis, there can [...]

With the current treatment that you are using on your patients, what are the expected outcomes?

By |November 9th, 2020|, |

At present, we can decide treatments based on experiences from large groups of patients with similar conditions.  However, the conclusions we make about the diseases and the treatments from studying the group as a whole do not always precisely apply to individual patients within the group; there is considerable variability in how individual patients [...]

What should we focus on while researching underlying causes for uveitis to help with the treatment (as parents)?

By |November 9th, 2020|, , |

Research is crucial to advancing knowledge about the causes, mechanisms, and treatment for uveitis. In all our research now, including our studies relating to uveitis and childhood arthritis, we ensure that parents and patients are represented on our research teams.  We feel it is important for patients and parents to contribute their ideas and [...]

What is known about ANA negative cases and ones that don’t show up strongly on tests but still show symptoms?

By |November 9th, 2020||

In children with the type of juvenile idiopathic arthritis (JIA; the word "idiopathic" means the cause is unknown) referred to as oligoarticular JIA (children with fewer than five joints involved; the name "oligo" comes from the Greek word meaning "few"),  the antinuclear antibody test (ANA) is positive in about 90% of children.  This type [...]

My doctor mentioned a 20% chance of uveitis among all JIA patients. If the patient has common characteristics such as young female and ANA positive, what does the probability of uveitis occurrence increase to for this subgroup?

By |November 6th, 2020|, |

Our Canadian research, looking at over 1,000 children newly diagnosed with JIA, has shown that the most important contributors to probability of uveitis are a positive ANA and being diagnosed at a young age.  Uveitis was most commonly seen in children with either oligoarthritis or polyarticular rheumatoid factor negative JIA. We also saw that [...]

October 2020

Can JIA and uveitis switch back and forth from joint pain to uveitis? Is this common?

By |October 28th, 2020|, , |

Children with JIA can develop uveitis at any time, even when their arthritis is not active.  For some children with JIA,  the arthritis inflammation becomes quiet, but they have continued uveitis requiring treatments. Similarly, arthritis can flare up at unpredictable times as well. The inflammation isn’t ‘switching back and forth’- the inflammation of JIA [...]

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