The uveal tract, which is the middle layer of the eye, is that part of the eye that becomes inflamed in uveitis. As shown in the figure the uveal tract extends from the very back of the eye to the very front, ending as the iris (the colored part of the eye surrounding the pupil). [...]
The course and outcomes of uveitis, including uveitis associated with juvenile arthritis, are variable; some children will have ongoing lingering disease activity and others can go into long-term control (remission). At the present time we can make decisions about treatments based on experiences from large groups of patients with similar conditions. However, the conclusions [...]
We don't have enough information to answer this question precisely but it is almost certainly true that with early diagnosis, careful monitoring and use of new medications the possibility of permanent remission increases. I wouldn't say children can "outgrow" uveitis exactly but with proper treatment the abnormal process that gives rise to the uveitis [...]
Assessing the microbiome is a complex, laboratory-based process. Doctors cannot effectively assess the microbiome by asking the patient questions or by findings on a physical examination. To effectively assess the intestinal microbiome a stool sample needs to be collected and processed in the laboratory so that the molecular and genetic characteristics of the bacteria [...]
This is a fascinating question and one for which there is accumulating but still minimal information. There is some evidence that maternal use of antibiotics either before or during pregnancy or at the time of labor might result in changes in the microbiome of the child born to that mother. There have been no [...]
Long term effects of uveitis can be minimized by prompt diagnosis, consistent monitoring, and appropriate use of medications. Some of the main effects that can occur and which we try to avoid with therapy include the following: Decrease in vision: When there is inflammation in the eye, such as occurs with uveitis, there can [...]
This is a very interesting and important question. Yes, uveitis can result from injury to the eye such as a blunt force to the eye or a foreign body in the eye. This usually results in iritis, which is inflammation of the colored part of the eye that surrounds the pupil. The iris is [...]
There are seven different types of Juvenile Idiopathic Arthritis.. It is uncommon for most forms of JIA to occur in siblings; children who present with the type of JIA referred to as ERA (Enthesitis Related Arthritis ; enthesitis refers to inflammation where ligaments and tendons insert onto bone), which tends to occur in older [...]
At present, we can decide treatments based on experiences from large groups of patients with similar conditions. However, the conclusions we make about the diseases and the treatments from studying the group as a whole do not always precisely apply to individual patients within the group; there is considerable variability in how individual patients [...]
Research is crucial to advancing knowledge about the causes, mechanisms, and treatment for uveitis. In all our research now, including our studies relating to uveitis and childhood arthritis, we ensure that parents and patients are represented on our research teams. We feel it is important for patients and parents to contribute their ideas and [...]
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