Long term effects of uveitis can be minimized by prompt diagnosis, consistent monitoring, and appropriate use of medications.  Some of the main effects that can occur and which we try to avoid with therapy include the following:

• Decrease in vision:  When there is inflammation in the eye, such as occurs with uveitis, there can be increased amounts of protein and inflammatory cells in the eye that interfere with light passing through the eye.  As a result, the ability to see clearly can be reduced.

• Cataracts:   A cataract is a painless clouding of the usually crystal clear lens of the eye. The lens sits behind the pupil of the eye as shown in the figure. Cataracts block light, making it difficult to see clearly.

• Synechiae:  Synechiae can occur as a result of uveitis. Synechiae are adhesions of the iris so the lens becomes stuck to either the lens below or the cornea in front (the cornea is a clear membrane window that lies in front of the pupil). When such adhesions occur, the iris will not move as freely.  Normally the iris will dilate (spread out) so the pupil enlarges when the environment is darker (allowing more light to enter the eye) and in bright light will constrict (come together) so the public gets smaller limiting the amount of light entering the eye.  When synechiae are present the movement of the iris is impeded and this can result in difficulty in adapting to light changes in the environment.

• Band Keratophathy: Band keratopathy is a line or band that appears across the center of the cornea. The band forms when calcium deposits collect in this area. Band keratopathy can reduce vision and sometimes causes eye irritation or redness.

• Increased eye pressure (glaucoma): Glaucoma can occur in some children with uveitis because the normal flow of fluids in the eye might be limited because of the inflamed tissues. Steroid medications can sometimes increase the eye pressure.