SRIs (serotonin-reuptake inhibitors) have been shown to offer benefit to some individuals for anxiety and depression.   Medications might be something to consider for those with moderate to severe symptoms and when there is substantial functional impact from the symptoms.  As for children/youth with rheumatic disease, you will need to talk with your prescribing doctor and pharmacist to determine if there are any contraindications to using an SSRI with any medications your child/teen might be taking.