The dose of methotrexate is generally prescribed by a child’s weight, with the dose calculated
based on a calculated body surface area. Your pediatric rheumatologist will suggest dosing
changes in your child’s medication depending on several factors including having a reasonable
trial of a new medication, such as Humira that your child just started. It may take several
months to see best benefit from Humira. Talk to your pediatric rheumatologist to get an idea
of how they will make decisions like changing the methotrexate dosing or administration
method.