There are no consensus guidelines regarding the benefit of routine follow up MRI testing in CRMO, and there is a lot of discussion among “CRMO” experts about this issue.   Many physicians treat based on symptoms and inflammatory signs;  other physicians are focused on treating radiograph (x-ray or MRI) lesions.  Since many CRMO lesions resolve over time, it is difficult to know whether continued treatment is necessary or provides additional benefit.  

We will likely only have answers to these questions over time, as our research networks collect more data in larger groups of patients.