0:00 – Introduction by Dr. Lori Tucker

3:00 – Dr. Lori Tucker introduces Sheila Grant (Parent Speaker) and Dr. Polly Ferguson

5:55 – CRMO Presentation by Dr. Polly Ferguson: What we know about the cause of CRMO

7:00 – Basics of Immunology

8:00 – Immune Activation and Inflammation

9:50 – Immune System Cells

10:30 – What causes immune activation in CRMO?

15:35 – Genetic Factors in CRMO

33:30 – CMO Mouse Experiment

39:00 – Why don’t we use IL-1 Inhibitors to treat CRMO?

41:15 – Treatments for CRMO (Blocking Pro-inflammatory Proteins)

44:55 – Misconceptions around CRMO (“What can I feed my child to make CRMO go away?”)

47:00 – Diet Advice for CRMO

48:10 – Closing and Acknowledgements

48:56 – Dr. Lori Tucker thanks Dr. Polly Ferguson and introduces Sheila’s Presentation

49:30 – Sheila’s Presentation about her family’s journey with CRMO

57:00 – Dr. Lori Tucker thanks Sheila

57:25 – Q&A session starts

58:05 – Why is it so hard to diagnose CRMO?

1:00:55 – How long does treatment need to continue? Is it possible to discontinue treatment? Are there risks of relapse if treatment stops?

1:04:15 – What percentage of kids will continue having problems with CRMO into adulthood or does this disease resolve?

1:09:30 – Can you have CRMO only in one site?

1:10:35 – Can you have CRMO and ERA in the same person?

1:12:05 – Do you have any advice for how parents can support their kids in learning how to advocate for themselves?

1:16:00 – Is there currently a way to identify if other family members are at risk?

1:16:53 – Conclusion of the Q&A session

1:17:53 – Closing Remarks