0:00 Welcome from C+F Executive Director, Jennifer Wilson

6:57 Introduction of Julie Beausoleil (patient speaker) and Pediatric Rheumatologist, Dr. Lori Tucker

7:43 Julie Beausoleil: A Journey Through Medication

8:40 My Story: Diagnosis + Background

10:34 My Medication Journey (Methotrexate, Enbrel)

17:57 Biologics Specific Information including side effects + missing medication

19:37 Other Considerations

23:25 Introduction of Dr. Lori Tucker

24:50 Dr. Tucker’s presentation on Biologics

25:49 What is a Biologic Medication?

26:15 Biologic Treatments you may know

26:33 Biologic Treatments commonly used in pediatric rheumatology

26:59 How are biologic treatments different from other medications?

28:06 Are biologics safe? What are the possible side effects?

30:15 Can my child on biologics get the COVID-19 Vaccine?

30:39 Do biologic treatments cause long term problems?

32:04 Biologics in the pediatric rheumatology community

32:25 Goals of treatments for children with rheumatic disease in 2021

32:47 When do we recommend a biologic treatment to your child

34:29 Biologics are part of the standard treatment for kids with JA

35:15 Biologics in JIA Capri Registry Dec. 2020

35:59 Are biologics effective in treating JIA?

37:14 Are biologics effective in treating systemic JIA (SJIA)?

38:06 Are biologics effective in treating uveitis and other inflammatory eye diseases?

38:41 What if the first biologic drug doesn’t work?

39:31 What’s a biosimilar?

41:55 Concerns about switching from a biologic or starting a biosimilar

43:29 Steps to starting a biologic/biosimilar medication

44:07 Biologics Coverage Options

44:45 Getting coverage for a biologic medication

45:25 Once your child is on a biologic

46:03 When can a biologic be stopped?

48:18 Question + Answer Period – Introduction to Dr. Roberta Berard (LHSC) and Dr. Nadia Luca who will join Dr. Tucker and Julie for the Q+A

49:20 How long can a child stay on a biologic safely? Why does a biologic work well for years and then all of a sudden stops working?

52:09 Is there a hierarchy of biologics when the initial biologic stops working?

54:15 Is there a maximum number of biologics that a patient can try?

55:30 Are there any considerations you take as a patient on biologics? Ie. Going back to school?

59:45 Generally, how do I give my child a biologic? When there are issues what can we do?

1:02:42 Julie, do you have any advice for parents with children who are struggling with medications?

1:04:35 Citrate- free humira

1:12:00 Julie, have you ever felt any issues or stress when adding medications to your routine? How do you manage?

1:13:38 Should we check for antibody levels?

1:12:35 Could a low neutrophil count be due to biologics? 

1:16:00 Is there any relationship between the length of time a child is on a biologic treatment and remission/ outgrowing JIA?

1:18:39 Is there a best biologic to treat ERA and will it actually take the pain away?

1:20:40 How would you guide or talk with families who are interested in a naturopathic approach over trying biologics?

1:23:00 What is next in biologics?

1:25:25 Julie, what advice do you have for families starting a biologic?